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1

A Mild Single-Step Reduction of Oximes to Amines 1

Leeds, James P., Kirst, Herbert A.

Journal:

Synthetic Communications

Year:

1988

Language:

english

File:

PDF, 188 KB

english, 1988

2

ChemInform Abstract: Synthesis and Insecticidal Activity of Spinosyn Analogues Functionally Altered at the 2′-, 3′-, and 4′-Positions of the Rhamnose Moiety.

Lawrence C. Creemer, Herbert A. Kirst, Jonathan W. Paschal, Thomas V. Worden

Journal:

Year:

2000

File:

PDF, 28 KB

2000

3

ChemInform Abstract: Chemical and Microbial Modifications of Spinosyn: Exploring Synergies Between Fermentation Microbiology and Organic Chemistry

Herbert A. Kirst, Lawrence C. Creemer, M. Chris Broughton, Mary L. B. Huber, Jan R. Turner

Journal:

Year:

2002

File:

PDF, 25 KB

2002

4

Synthesis and in vitro Antimicrobial Activity of 3-Keto 16-Membered Macrolides Derived from Tylosin.

Lawrence C. Creemer, John E. Toth, Herbert A. Kirst

Journal:

Year:

2002

File:

PDF, 27 KB

2002

5

ChemInform Abstract: The Spinosyn Family of Insecticides: Realizing the Potential of Natural Products Research

Herbert A. Kirst

Journal:

Year:

2010

File:

PDF, 15 KB

2010

6

A83543A-D, unique fermentation-derived tetracyclic macrolides

Herbert A. Kirst, Karl H. Michel, James W. Martin, Lawrence C. Creemer, Eddie H. Chio, Raymond C. Yao, Walter M. Nakatsukasa, LaVerne D. Boeck, John L. Occolowitz, Jonathan W. Paschal, Jack B. Deeter,

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 152 KB

english, 1991

7

Control of site-specific substitution of aminoglycosides by transition metal cations

Herbert A. Kirst, Brenda A. Truedell, John E. Toth

Journal:

Tetrahedron Letters

Year:

1981

Language:

english

File:

PDF, 199 KB

english, 1981

8

Synthesis and evaluation of a series of 1,4-Diarylbutadienes for anticoccidial activity

Jennifer L Gage, Herbert A Kirst, Deirdre O'Neil, Bridget A David, Charles K Smith II, Sharon A Naylor

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 267 KB

english, 2003

9

Engineering Conferences International (ECI) Natural Products Discovery and Production II

Kirst, Herbert A

Journal:

The Journal of Antibiotics

Year:

2008

File:

PDF, 151 KB

2008

10

11th International Conference on the Chemistry of Antibiotics and other Bioactive Compounds (ICCA-11) Donostia—San Sebastian, Spain 29 September–2 October 2009

Kirst, Herbert A

Journal:

The Journal of Antibiotics

Year:

2009

Language:

english

File:

PDF, 289 KB

english, 2009

11

The spinosyn family of insecticides: realizing the potential of natural products research

Kirst, Herbert A

Journal:

The Journal of Antibiotics

Year:

2010

Language:

english

File:

PDF, 600 KB

english, 2010

12

Genetic engineering of aminodeoxyhexose biosynthesis in Streptomyces fradiae

Butler, Andrew R., Bate, Neil, Kiehl, Douglas E., Kirst, Herbert A., Cundliffe, Eric

Journal:

Nature Biotechnology

Year:

2002

Language:

english

File:

PDF, 2.20 MB

english, 2002

13

The Application of Artificial Neural Networks to the Identification of New Spinosoids with Improved Biological Activity toward Larvae of Heliothis virescens

Thomas C. Sparks, Peter B. Anzeveno, Jacek G. Martynow, James M. Gifford, Mark B. Hertlein, Thomas V. Worden, Herbert A. Kirst

Journal:

Pesticide Biochemistry and Physiology

Year:

2000

Language:

english

File:

PDF, 144 KB

english, 2000

14

The antibacterial and NMDA receptor activating properties of aminoglycosides are dissociable

Scott C Harvey, Xia Li, Phil Skolnick, Herbert A Kirst

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 144 KB

english, 2000

15

Developing new antibacterials through natural product research

Kirst, Herbert A

Journal:

Expert Opinion on Drug Discovery

Year:

2013

Language:

english

File:

PDF, 536 KB

english, 2013

16

Prologue to the Special Issue on Synthesis

Kirst, Herbert A, Takahashi, Yoshikazu

Journal:

The Journal of Antibiotics

Year:

2013

Language:

english

File:

PDF, 62 KB

english, 2013

17

Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics

Kirst, Herbert A., Toth, John E., Debono, Manuel, Willard, Kevin E., Truedell, Brenda A., Ott, John L., Counter, Fred T., Felty-Duckworth, Anna M., Pekarek, Robert S.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 1.45 MB

english, 1988

18

The Stereochemical Outcome of Electrophilic Addition Reactions on the 5,6-Double Bond in the Spinosyns

De Amicis, Carl V., Graupner, Paul R., Erickson, Jon A., Paschal, Jonathon W., Kirst, Herbert A., Creemer, Lawrence C., Fanwick, Phillip E.

Journal:

Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 68 KB

english, 2001

19

Studies on the total synthesis of steroidal antibiotics. 2. Two convergent schemes for the synthesis of tetracyclic intermediates

Ireland, Robert E., Beslin, Pierre, Giger, Rudolf, Hengartner, Urs, Kirst, Herbert A., Maag, Hans

Journal:

Journal of Organic Chemistry

Year:

1977

Language:

english

File:

PDF, 1.47 MB

english, 1977

20

Identification and Synthesis of an Oxidation Product of Tilmicosin

Willard, Kevin E., Kirst, Herbert A., Leeds, James P., Readnour, Robin S., Klink, Paul R., Cleveland, Christine M., Kiehl, Douglas E.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1998

Language:

english

File:

PDF, 182 KB

english, 1998

21

New macrolide, lincosaminide and streptogramin B antibiotics

Kirst, Herbert A

Journal:

Expert Opinion on Therapeutic Patents

Year:

2010

Language:

english

File:

PDF, 771 KB

english, 2010

22

Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli

Allen, Norris E., Alborn, William E., Kirst, Herbert A., Toth, John E.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 1.17 MB

english, 1987

23

Synthesis of ring-contracted derivatives of erythromycin

Kirst, Herbert A., Wind, Julie A., Paschal, Jonathan W.

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 495 KB

english, 1987

24

Synthesis and structure-activity relationships of new 9-N-alkyl derivatives of 9(S)-erythromycylamine

Kirst, Herbert A., Wind, Julie A., Leeds, James P., Willard, Kevin E., Debono, Manuel, Bonjouklian, Rosanne, Greene, James M., Sullivan, Kevin A., Paschal, Jonathan W.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 1.23 MB

english, 1990

25

Chemistry of A83543A Derivatives. 1. Oxidations and Reductions of A83543A Aglycon

Martynow, Jacek G., Kirst, Herbert A.

Journal:

Journal of Organic Chemistry

Year:

1994

Language:

english

File:

PDF, 2.71 MB

english, 1994

26

New method for the synthesis of macrolides

Corey, E. J., Kirst, Herbert A.

Journal:

Journal of the American Chemical Society

Year:

1972

Language:

english

File:

PDF, 261 KB

english, 1972

27

Identification and Synthesis of Products Isolated during Metabolism Studies of Tilmicosin

Kirst, Herbert A., Donoho, Alvin L., Creemer, Lawrence C., Wind, Julie A., Berry, Donnis M., Occolowitz, John L., Paschal, Jonathan W.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1994

Language:

english

File:

PDF, 368 KB

english, 1994

28

Synthesis and in Vitro Evaluation of New Wortmannin Esters: Potent Inhibitors of Phosphatidylinositol 3-Kinase

Creemer, Lawrence C., Kirst, Herbert A., Vlahos, Chris J., Schultz, Richard M.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 166 KB

english, 1996

29

Synthesis of ring-contracted derivatives of erythromycin [Erratum to document cited in CA107(19):175746c]

Kirst, Herbert A., Wind, Julie A., Paschal, Jonathan W.

Journal:

Journal of Organic Chemistry

Year:

1988

Language:

english

File:

PDF, 112 KB

english, 1988

30

Antibiotics versus resistant bacteria: a continual challenge

Kirst, Herbert A

Journal:

Expert Opinion on Therapeutic Patents

Year:

2010

Language:

english

File:

PDF, 147 KB

english, 2010

31

Macrolide antibiotics in food-animal health

Kirst, Herbert A

Journal:

Expert Opinion on Investigational Drugs

Year:

1997

Language:

english

File:

PDF, 327 KB

english, 1997

32

Recent developments with macrolide antibiotics

Kirst, Herbert A

Journal:

Expert Opinion on Therapeutic Patents

Year:

1998

Language:

english

File:

PDF, 163 KB

english, 1998

33

13th International Conference on the Chemistry of Antibiotics and Other Bioactive Compounds (ICCA-13)

Kirst, Herbert A

Journal:

The Journal of Antibiotics

Year:

2014

Language:

english

File:

PDF, 952 KB

english, 2014

34

Recent derivatives from smaller classes of fermentation-derived antibacterials

Kirst, Herbert A

Journal:

Expert Opinion on Therapeutic Patents

Year:

2012

Language:

english

File:

PDF, 974 KB

english, 2012

35

12th International Conference on the Chemistry of Antibiotics and other Bioactive Compounds (ICCA-12)

Kirst, Herbert A

Journal:

The Journal of Antibiotics

Year:

2012

Language:

english

File:

PDF, 155 KB

english, 2012

36

New macrolides: expanded horizons for an old class of antibiotics

KIRST, HERBERT A.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

1991

Language:

english

File:

PDF, 297 KB

english, 1991

37

Macrolide Antibiotics || Pharmacokinetics/pharmacodynamics of macrolides

Schönfeld, Wolfgang, Kirst, Herbert A.

Year:

2002

Language:

english

File:

PDF, 1.43 MB

english, 2002

38

Macrolide Antibiotics || Mechanisms of resistance to macrolides, lincosamides, and ketolides

Schönfeld, Wolfgang, Kirst, Herbert A.

Year:

2002

Language:

english

File:

PDF, 4.59 MB

english, 2002

39

Circumventing resistance to anti-infective agents

Kirst, Herbert A

Journal:

Expert Opinion on Pharmacotherapy

Year:

2015

Language:

english

File:

PDF, 401 KB

english, 2015

40

Kirk-Othmer Encyclopedia of Chemical Technology || Antibiotics, Macrolides

Year:

2000

Language:

english

File:

PDF, 328 KB

english, 2000

41

Effects of LY267108, an erythromycin analogue derivative, on lower esophageal sphincter function in the cat

Greenwood, Beverley, Dieckman, Donna, Kirst, Herbert A., Gidda, Jaswant S.

Journal:

Gastroenterology

Year:

1994

Language:

english

File:

PDF, 614 KB

english, 1994

42

[Progress in Medicinal Chemistry] Volume 30 || 2 Semi-Synthetic Derivatives of Erythromycin

Kirst, Herbert A.

Year:

1993

Language:

english

File:

PDF, 1.70 MB

english, 1993

43

Structure of althiomycin.

KIRST, HERBERT A., SZYMANSKI, EDWARD F., DORMAN, DOUGLAS E., OCCOLOWITZ, JOHN L., JONES, NOEL D., CHANEY, MICHAEL O., HAMILL, ROBERT L., HOEHN, MARVIN M.

Journal:

The Journal of Antibiotics

Year:

1975

Language:

english

File:

PDF, 2.57 MB

english, 1975

44

Novel fermentation products from Streptomyces fradiae: X-ray crystal structure of 5-O-mycarosyltylactone and proof of the absolute configuration of tylosin.

JONES, NOEL D., CHANEY, MICHAEL O., KIRST, HERBERT A., WILD, GENE M., BALTZ, RICHARD H., HAMILL, ROBERT L., PASCHAL, JONATHAN W.

Journal:

The Journal of Antibiotics

Year:

1982

Language:

english

File:

PDF, 2.73 MB

english, 1982

45

Structure of the Spiroketal-macrolide Ossamycin.

KIRST, HERBERT A., MYNDERSE, JON S., MARTIN, JAMES W., BAKER, PATRICK J., PASCHAL, JONATHAN W., STEiNER, JORGE L. Rios, LoBKovsKY, EMIL, CLARDY, JON

Journal:

The Journal of Antibiotics

Year:

1996

Language:

english

File:

PDF, 450 KB

english, 1996

46

Synthesis, Antimicrobial Activity and In vivo Fluorine NMR of a Hexafluorinated Derivative of Tilmicosin.

CREEMER, LAWRENCE C., KIRST, HERBERT A., SHRYOCK, THOMAS R., CAMPBELL, JACK B., WEBB, ANDREW G.

Journal:

The Journal of Antibiotics

Year:

1995

Language:

english

File:

PDF, 297 KB

english, 1995

47

Conversion of Spinosyn A and Spinosyn D to Their Respective 9- and 17-Pseudoaglycones and Their Aglycones.

CREEMER, LAWRENCE C., KIRST, HERBERT A., PASCHAL, JONATHAN W.

Journal:

The Journal of Antibiotics

Year:

1998

Language:

english

File:

PDF, 731 KB

english, 1998

48

Synthesis and Insecticidal Activity of Spinosyn Analogs Functionally Altered at the 2'-, 3'- and 4'-Positions of the Rhamnose Moiety.

CREEMER, LAWRENCE C., KIRST, HERBERT A., PASCHAL, JONATHAN W., WORDEN, THOMAS V.

Journal:

The Journal of Antibiotics

Year:

2000

Language:

english

File:

PDF, 530 KB

english, 2000

49

Synthesis and In Vitro Antimicrobial Activity of 3-Keto 16-Membered Macrolides Derived From Tylosin.

CREEMER, LAWRENCE C., TOTH, JOHN E., KIRST, HERBERT A.

Journal:

The Journal of Antibiotics

Year:

2002

Language:

english

File:

PDF, 1.27 MB

english, 2002

50

Structure elucidation of A58365A and A58365B, angiotensin converting enzyme inhibitors produced by Streptomyces chromofuscus.

HUNT, ANN H., MYNDERSE, JON S., SAMLASKA, SUSAN K., FUKUDA, DAVID S., MACIAK, GEORGE M., KIRST, HERBERT A., OCCOLOWITZ, JOHN L., SWARTZENDRUBER, JOHN K., JONES, NOEL D.

Journal:

The Journal of Antibiotics

Year:

1988

Language:

english

File:

PDF, 453 KB

english, 1988